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. 2014 Sep 4;9(9):e105653. doi: 10.1371/journal.pone.0105653

Table 1. Estimated probability of virologic suppression and absolute CD4+ cell count change from baseline.

Estimated Probability of Virologic Suppression at week 48 Mean (95% CrI) Estimated CD4+ cell count change from baseline to week 48 Mean (95% CrI)
Third agent TDF/FTC ABC/3TC Other Backboneunadjusted TDF/FTC ABC/3TC Other Backboneunadjusted
N = 26 studies N = 26 studies N = 26 studies N = 22 studies N = 28 studies N = 28 studies N = 28 studies N = 24 studies
ATV/r 0.74 (0.68,0.79) 0.72 (0.66,0.78) 0.68 (0.62,0.74) 0.71 (0.66,0.76) 188.5 (176.5,200.6) 204.7 (191.4,218.4) 151.5 (134.2,169.0) 181.4 (171.0,191.8)
DRV/r 0.76 (0.68,0.83) 0.74 (0.66,0.81) 0.71 (0.62,0.78) 0.73 (0.65,0.80) 197.5 (175.4,219.4) 213.8 (191.8,235.3) 160.5 (135.8,185.1) 194.5 (173.6,215.4)
DTG 0.86 (0.81,0.90) 0.85 (0.80,0.88) 0.82 (0.77,0.87) 0.84 (0.79,0.87) 224.7 (205.6,243.7) 240.9 (224.3,257.7) 187.7 (166.5,209.1) 226.8 (210.7,242.6)
EFV 0.77 (0.74,0.79) 0.75 (0.72,0.78) –0.72 (0.68,0.75) 0.75 (0.74,0.76) 186.8 (179.5,194.0) 203.0 (193.2,212.9) 149.7 (135.0,164.5) 179.1 (175.1,183.1)
EVG/c 0.80 (0.74,0.85) 0.79 (0.72,0.84) 0.76 (0.69,0.82) 0.78 (0.72,0.83) 203.3 (184.8,221.7) 219.5 (200.1,238.7) 166.3 (144.2,189.0) 196.1 (178.3,213.4)
LPV/r 0.70 (0.65,0.76) 0.68 (0.62,0.74) 0.65 (0.58,0.71) 0.68 (0.62,0.73) 198.0 (181.7,214.5) 214.2 (197.5,231.1) 161.0 (140.5,181.6) 192.1 (176.8,207.5)
RAL 0.83 (0.77,0.87) 0.81 (0.75,0.86) 0.78 (0.72,0.84) 0.80 (0.75,0.85) 221.3 (200.5,242.2) 237.5 (217.7,257.5) 184.2 (160.8,207.8) 219.6 (200.4,239.1)
RPV 0.80 (0.76,0.84) 0.79 (0.74,0.83) 0.76 (0.71,0.80) 0.78 (0.75,0.82) 201.4 (187.3,215.2) 217.6 (202.0,232.8) 164.3 (145.8,183.3) 193.8 (181.1,206.5)

Note: Estimates derived from this meta-analysis may differ from that of any given RCT, due to statistical aggregation of data from several trials.