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Terms and abbreviations
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Definitions
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| Rapid virologic response (RVR) |
Undetectable viral RNA at week 4 of treatment |
| Early virologic response (EVR) |
≥2 log decrease in viral count at week 12 |
| Partial early virologic response (pEVR) |
EVR with detectable viral RNA at week 12 |
| Complete early virologic response (cEVR) |
EVR with undetectable viral RNA at week 12 |
| Null response (NR) |
Not achieving 2 log decrease in viral count at week 12 |
| Breakthrough |
Reappearance of viral RNA during treatment after viral RNA has become negative |
| End-of-treatment response (ETR) |
Undetectable viral RNA at end of treatment |
| Sustained virologic response (SVR) |
Undetectable viral RNA 24 weeks after end of treatment |
| Recurrence (relapse) |
Reappearance of viral RNA within 24 weeks after end of treatment in a patient with ETR |