Table 4. elationship between PMPMEase staining intensity and clinicopathological features of the prostate cancer tissues used.
| Characteristics | PMPMEase Staining Intensity, N (%) | p-value | |||||
|---|---|---|---|---|---|---|---|
| 1–100 Trace | 101–200 Weak | 201–300 Intermediate | 301–400 Strong | 401–500 Very strong | Mean Scores | ||
| Normal | 4 (50.0) | 2 (25.0) | 3 (25.0) | 0 | 0 | 162.5 ± 37.50 | |
| NAT | 0 | 3 (25.0) | 5 (41.7) | 3 (25.0) | 1 (8.3) | 285.4 ± 23.93 | 0.0094 |
| Pathology diagnosis | |||||||
| Transitional cell carcinoma | 0 | 0 | 0 | 2 (100) | 0 | 391.7 ± 8.3 | 0.0001* |
| Adenocarcinomas | 0(0) | 5(5.4) | 17 (18.4) | 45(48.9) | 25 (27.2) | 348.1 ± 8.3 | 0.0001 |
| Grade | |||||||
| 1 | 0 | 1(11.1) | 0 | 2(22.2) | 6(66.7) | 400.0 ± 26.8 | 0.0001 |
| 2 | 0 | 1 (2.7) | 9 (24.3) | 19 (51.4) | 8(21.6) | 333.4 ± 11.3 | 0.0001 |
| 2-3 | 0 | 0 | 0 | 3 (100) | 0 | 366.7 ± 15.02 | 0.0001 |
| 3 | 0 | 2 (6.7) | 6 (20.0) | 16 (53.3) | 6 (20) | 337.9 ± 14.4 | 0.0001 |
| 4 | 0 | 1 (10) | 2 (20) | 4 (40) | 3 (30) | 335.0 ± 30.2 | 0.0001 |
| Undetermined | 0 | 0 | 0 | 0 | 5 (100) | 455.6 ± 12.97 | 0.0001 |
| Gleason grade | |||||||
| 1 | 0 | 0 | 0 | 4 (44.4) | 5(55.6) | 410.1 ± 14.10 | 0.0001 |
| 2 | 0 | 0 | 2 (28.6) | 3 (42.9) | 2 (28.6) | 360.7 ± 32.89 | 0.0001 |
| 3 | 0 | 1 (4.0) | 3 (12) | 17 (68.0) | 4 (16.0) | 343.5 ± 12.42 | 0.0001 |
| 4 | 0 | 1 (4.3) | 7 (30.4) | 10 (45.3) | 5 (21.7) | 325.6 ± 16.48 | 0.0001 |
| 5 | 0 | 3 (11.5) | 5 (19.2) | 11 (42.3) | 7 (26.9) | 333.2 ± 17.81 | 0.0001 |
| Undetermined | 0 | 0 | 0 | 0 | 2 (100) | 475 ± 25.0 | 0.0001 |
| Gleason score | |||||||
| 1+1 | 0 | 0 | 0 | 1 (25.0) | 3 (75.0) | 444.5 ± 26.46 | 0.0001 |
| 1+2 | 0 | 0 | 0 | 1 (100.0) | 0 | 0 | |
| 1+3 | 0 | 0 | 0 | 1 (100.0) | 0 | 0 | |
| 1+4 | 0 | 1 (100.0) | 0 | 0 | 0 | 0 | |
| 2+2 | 0 | 1 (12.5) | 0 | 3 (37.5) | 4 (50.0) | 389.1 ± 28.59 | 0.0001 |
| 2+3 | 0 | 0 | 1 (9.1) | 6 (54.5) | 4 (36.4) | 381.8 ± 15.84 | 0.0001 |
| 2+4 | 0 | 0 | 0 | 0 | 1 (100.0) | 0 | |
| 2+5 | 0 | 0 | 0 | 0 | 1 (100.0) | 0 | |
| 3+2 | 0 | 0 | 1 (100.0) | 0 | 0 | 0 | |
| 3+3 | 0 | 0 | 4 (28.6) | 8 (57.1) | 2 (14.3 | 331.3 ± 16.04 | 0.0001 |
| 3+4 | 0 | 0 | 1 (16.7) | 4 (66.7) | 1 (16.7) | 335.4 ± 26.30 | 0.0043 |
| 3+5 | 0 | 0 | 0 | 2 (66.7) | 1(33.3) | 362.5 ± 26.02 | 0.0131 |
| 4+2 | 0 | 0 | 1 (100.0) | 0 | 0 | 0 | |
| 4+3 | 0 | 0 | 3 (60.0) | 2 (40.0) | 0 | 300 ± 30.87 | 0.0266 |
| 4+4 | 0 | 0 | 4 (33.3) | 5 (41.7) | 3 (25) | 342.7 ± 23.0 | 0.0001 |
| 4+5 | 0 | 0 | 0 | 3 (100.0) | 0 | 358.3 ± 4.17 | 0.0129 |
| 5+3 | 0 | 0 | 0 | 2 (100.0) | 0 | 350 ± 12.50 | |
| 5+4 | 1 (25.0) | 1 (25.0) | 2 (50.0) | 0 | 340.6 ± 58. | 0.0243 | |
| 5+5 | 2 (15.4) | 2 (15.4) | 6(46.2) | 3 (23.1) | 327.9 ± 26.93 | 0.0001 | |
| Tumour size | |||||||
| 1 | 0 | 0 | 0 | 0 | 2 (100) | 451 ± 14.0 | |
| 2 | 0 | 4 (5.1) | 16 (20.3) | 40 (50.6) | 19 (24.1) | 342.2 ± 8.7 | 0.0001 |
| 3 | 0 | 0 | 1 (16.7) | 4 (66.7) | 1 (16.7) | 362.5 ± 26.0 | 0.0001 |
| 4 | 0 | 1 (14.3) | 0 | 3 (42.9) | 3 (42.9) | 383.9 ± 37.7 | 0.0001 |