Figure 4. Microarray analysis of stress-shielded wounds. (A) Hierarchical clustering of regulated genes from wounds under stress-shielding or natural stress. Individual genes are clustering according to the dendrogram on the left, and samples correspond to columns in the heatmap on the right (n = 2 per group). Yellow and blue indicate up- and downregulation, respectively. (B) Canonical pathways significantly enriched for among genes whose expression was significantly upregulated in stress-shielded wounds compared with natural stress wounds. (C) Canonical pathways significantly enriched for among genes whose expression was significantly downregulated in stress-shielded wounds compared with natural stress wounds.