Table 2.
Adjusted ORs (95% CIs)a for glioma and meningioma in relation to categorical indicators of occupational ELF-MF exposure overall (1-year lag), INTEROCC study, 2000–2004, Australia, Canada, France, Germany, Israel, New Zealand, and United Kingdom
Exposure Metric | Glioma | Meningioma | ||||
---|---|---|---|---|---|---|
Cases | Controls | OR (95% CI)a | Cases | Controls | OR 95% CIa | |
Cumulative Exposure (μT-years) | ||||||
< 2.11 | 475 | 1,334 | 1.00 (ref) | 473 | 1,265 | 1.00 (ref) |
2.11–< 3.40 | 454 | 1,327 | 1.00 (0.85, 1.18) | 465 | 1,278 | 0.96 (0.82, 1.13) |
3.40–< 5.00 | 441 | 1,344 | 0.93 (0.78, 1.11) | 414 | 1,295 | 0.84 (0.70, 0.99) |
5.00–<7.50 | 370 | 808 | 1.07 (0.88, 1.31) | 290 | 783 | 1.05 (0.86, 1.29) |
7.50+ | 199 | 540 | 0.80 (0.63, 1.00) | 180 | 524 | 0.89 (0.70, 1.12) |
p-value trend | 0.08 | 0.51 | ||||
Average Exposure (μT) | ||||||
< 0.11 | 423 | 1,268 | 1.00 (ref) | 426 | 1,224 | 1.00 (ref) |
0.11–< 0.13 | 398 | 1,273 | 0.96 (0.82, 1.13) | 419 | 1,244 | 0.94 (0.79, 1.10) |
0.13–<0.17 | 551 | 1,411 | 1.04 (0.89, 1.22) | 510 | 1,345 | 1.18 (1.00, 1.38) |
0.17–<0.24 | 330 | 856 | 0.95 (0.80, 1.14) | 262 | 809 | 1.03 (0.85, 1.25) |
0.24+ | 237 | 545 | 1.00 (0.82, 1.23) | 205 | 523 | 1.08 (0.87, 1.33) |
p-value trend | 0.99 | 0·41 | ||||
Maximum Exposed Job (μT) | ||||||
< 0.13 | 453 | 1,370 | 1.00 (ref) | 505 | 1,341 | 1.00 (ref) |
0.13–< 0.17 | 458 | 1,290 | 0.92 (0.79, 1.08) | 439 | 1,247 | 1.03 (0.88, 1.20) |
0.17–< 0.23 | 430 | 1,202 | 0.85 (0.73, 1.00) | 362 | 1,146 | 0.98 (0.83, 1.16) |
0.23–<0.62 | 382 | 947 | 0.92 (0.78, 1.09) | 286 | 891 | 1.01 (0.84, 1.21) |
0.62+ | 216 | 544 | 0.80 (0.65, 0.98) | 230 | 520 | 1.15 (0.94, 1.42) |
p-value trend | 0.08 | 0·16 | ||||
Exposure Duration (years) | ||||||
< 5 | 1,333 | 3,849 | 1.00 (ref) | 1,324 | 3,716 | 1.00 (ref) |
5–< 15 | 295 | 805 | 0.90 (0.77, 1.05) | 255 | 754 | 0.99 (0.84, 1.17) |
15–< 25 | 142 | 371 | 0.94 (0.76, 1.16) | 104 | 353 | 0.85 (0.67, 1.08) |
25+ | 169 | 328 | 1.22 (0.99, 1.51) | 139 | 322 | 1.30 (1.03, 1.64) |
p-value trend | 0.26 | 0.20 |
OR estimated using conditional logistic regression models stratified by country, region, sex, and 5-year age group at the reference date and adjusted for level of educational attainment. Cut points based on the 25th, 50th, 75th, and, 90th percentile of the control exposure distribution. Tests for linear trend used Wald x2 tests, with categorical medians modeled as ordinal variables.