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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Cancer Prev Res (Phila). 2014 Jul 3;7(9):958–967. doi: 10.1158/1940-6207.CAPR-14-0126

Figure 2. RSK2 and MSK1 play an important role in anchorage-independent and-dependent skin cancer cell growth.

Figure 2

Knocking down RSK2 or MSK1 expression inhibits A431 anchorage-independent cell growth and proliferation. A431 cells stably expressing sh-mock, sh-RSK2, sh-MSK1 or sh-RSK2/sh-MSK1 were evaluated for colony growth under anchorage-independent conditions (A). Proliferation of A431 cells stably expressing sh-mock, sh-RSK2, sh-MSK1 or sh-RSK2/sh-MSK1 was measured by MTS assay at the indicated time point (B). Data are shown as mean values ± S.D. obtained from triplicate experiments. Significant differences were evaluated using one-way ANOVA and the asterisks indicate a significant effect (*, p < 0.05; **, p <0.01).