Table 5. Nicotine and exhaled carbon monoxide measurements by cigarette type and condition.
| Plasma nicotine (ng/mL) | Exhaled CO (ppm) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Cigarette type | Condition | PRE | POST | p | BOOST | PRE | POST | p | BOOST |
| RYO (n=34) | NR | 12.3 (8.1) | 26.6 (13.3) | † | 14.3 (10.2) | 29 (17) | 34 (16) | NS | 4 (3) |
| ABS | 2.4 (2.0) | 21.8 (16.6) | † | 19.4 (16.9) | 9 (3) | 14 (4) | NS | 6 (3) | |
| INT | 16.2 (8.1) | 25.7 (12.2) | † | 9.5 (8.2) | 32 (12) | 36 (12) | NS | 4 (3) | |
|
| |||||||||
| ABS<NR†; INT† | - | ABS>INT† | ABS<NR†; INT† | ABS<NR†; INT† | ABS>INT* | ||||
|
| |||||||||
| PMM (n=23) | NR | 13.3 (7.1) | 33.1 (19.8) | † | 19.8 (18.3) | 27 (13) | 32 (11) | NS | 5 (3) |
| ABS | 2.8 (1.9) | 20.4 (17.4) | † | 17.6 (17.8) | 9 (2) | 15 (3) | NS | 6 (3) | |
| INT | 22.1 (11.9) | 31.0 (17.7) | NS | 8.9 (17.9) | 36 (13) | 40 (13) | NS | 4 (3) | |
|
| |||||||||
| ABS<NR†; INT† INT>NR† | - | - | ABS<NR†; INT† INT>NR† | ABS<NR†; INT† INT>NR† | ABS>INT* | ||||
|
| |||||||||
| FM (n=20) | NR | 10.3 (7.5) | 29.1 (13.1) | † | 18.8 (12.2) | 22 (14) | 39 (26) | † | 9 (5) |
| ABS | 1.6 (1.0) | 23.5 (11.9) | † | 21.9 (11.6) | 8 (3) | 16 (4) | NS | 9 (3) | |
| INT | 18.2 (9.2) | 31.0 (12.2) | † | 12.2 (9.9) | 33 (13) | 44 (20) | NS | 7 (5) | |
|
| |||||||||
| ABS<NR†; INT† INT>NR† | - | ABS>INT* | ABS<NR†; INT† INT>NR† | ABS<NR†; INT† | - | ||||
Arithmetic means with standard deviations are presented RYO – roll your own; PMM – personal machine made; FM – factory made; PRE – biomarker level before smoking; POST – biomarker level after smoking; BOOST – difference between biomarker levels after and before smoking; NR – No restrictions; ABS – Overnight tobacco abstinence (12h, exhaled CO≤12ppm); INT – intense smoking; p – post-hoc ANOVA test