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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2014 Jul 10;23(9):1773–1782. doi: 10.1158/1055-9965.EPI-14-0427

Table 2.

Linear regression analysis of the predictors of the nicotine metabolite ratio (NMR) in the total sample (N=1672)

Nicotine Metabolite Ratio (NMR)
R2 = 0.076a; P <0.001
Predictor B Standard Error β P value % Variationb
Ethnicityc 0.071 0.011 0.162 <0.001 2.3
Genderd,e 0.057 0.010 0.136 <0.001 1.7
Birth control pill use 0.036 0.050 0.017 0.47 0.03
Hormone replacement therapy use 0.114 0.054 0.050 0.036 0.24
Body mass index −0.003 0.001 −0.108 <0.001 1.1
Alcohol use (# drinks/week) 0.003 0.001 0.070 0.004 0.46
Cigarettes per day 0.002 0.001 0.062 0.012 0.36
a

Together the predictors account for 7.6% of the variation in NMR

b

Calculated by squaring the part correlation coefficient (not shown), and multiplying by 100

c

African Americans and Caucasians were coded as ‘0’ and ‘1’, respectively, in the model

d

Males and females were coded as ‘0’ and ‘1’, respectively, in the model

e

When we restricted the model to females only (N=756), to further examine the effect of birth control pill and hormone replacement therapy use, the predictors (gender is excluded) together explained 6.6% of the variation in NMR. The standardized beta values for birth control pill and hormone replacement therapy use were 0.025 (P=0.48) and 0.069 (P=0.052), respectively, in the female-only group. They uniquely contributed 0.06% and 0.48% of the variation in NMR, respectively, in females.