Table 3.
Observed condition means (%) | Work vs. Methadone | Work vs. Abstinence | Methadone vs. Abstinence | ||||||
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Work | Methadone | Abstine nce | p | OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | |
Induction period | |||||||||
Opiate negative | |||||||||
Missing positive | 32 | 30 | 22 | 0.78 | 1.10 (0.57-2.13) | 0.16 | 1.66 (0.82-3.35) | 0.24 | 1.51 (0.76-2.99) |
Missing missing | 37 | 34 | 26 | 0.72 | 1.13 (0.58-2.21) | 0.16 | 1.67 (0.82-3.40) | 0.27 | 1.48 (0.74-2.95) |
Cocaine negative | |||||||||
Missing positive | 33 | 35 | 31 | 0.86 | 0.93 (0.41-2.10) | 0.80 | 1.11 (0.48-2.58) | 0.66 | 1.20 (0.54-2.67) |
Missing missing | 38 | 39 | 36 | 0.98 | 0.99 (0.43-2.30) | 0.75 | 1.15 (0.49-2.73) | 0.72 | 1.16 (0.51-2.66) |
Opiate & cocaine negative | |||||||||
Missing positive | 19 | 17 | 11 | 0.72 | 1.16 (0.51-2.68) | 0.21* | 1.81 (0.72-4.55) | 0.34 | 1.55 (0.62-3.87) |
Missing missing | 22 | 19 | 13 | 0.71 | 1.18 (0.51-2.73) | 0.22* | 1.79 (0.71-4.51) | 0.37 | 1.52 (0.61-3.79) |
Days in attendance | 75 | 86 | 83 | 0.14 | 0.65 (0.87-2.72) | 0.03* | 0.52 (1.08-3.48) | 0.46 | 0.80 (0.69-2.31) |
Collected samples | 86 | 89 | 86 | 0.52 | 0.79 (0.63-2.54) | 0.93 | 1.03 (0.49-1.91) | 0.45 | 1.30 (0.39-1.52) |
Intervention evaluation period | |||||||||
Opiate negative | |||||||||
Missing positive | 43 | 50 | 65 | 0.37 | 0.75 (0.36-1.55) | 0.01* | 0.40 (0.39-0.40) | 0.05 | 0.53 (0.28-1.00) |
Missing missing | 57 | 65 | 78 | 0.25 | 0.73 (0.44-1.19) | 0.01* | 0.37 (0.37-0.37) | 0.03* | 0.51 (0.28-0.93) |
Cocaine negative | |||||||||
Missing positive | 25 | 44 | 48 | 0.03* | 0.41 (0.39-0.44) | 0.01* | 0.35 (0.34-0.35) | 0.63 | 0.84 (0.42-1.69) |
Missing missing | 35 | 55 | 56 | 0.04* | 0.45 (0.42-0.48) | 0.04* | 0.44 (0.41-0.48) | 0.96 | 0.98 (0.48-2.02) |
Opiate & cocaine negative | |||||||||
Missing positive | 21 | 35 | 46 | 0.07* | 0.49 (0.43-0.56) | 0.01* | 0.31 (0.31-0.32) | 0.19 | 0.64 (0.33-1.25) |
Missing missing | 29 | 44 | 51 | 0.08* | 0.52 (0.45-0.61) | 0.01* | 0.39 (0.38-0.40) | 0.42 | 0.76 (0.39-1.48) |
Days in attendance | 68 | 70 | 70 | 0.78 | 0.90 (0.53-2.33) | 0.88 | 0.95 (0.51-2.19) | 0.89 | 1.05 (0.46-1.95) |
Collected samples | 72 | 74 | 77 | 0.81 | 0.91 (0.51-2.38) | 0.51 | 0.76 (0.59-2.92) | 0.66 | 0.84 (0.55-2.60) |
Note. Bold values indicate statistical significance. Asterisks indicate statistically significant differences between conditions in analyses adjusted for the three stratification variables (i.e., enrolled in methadone treatment, greater than 50% cocaine negative urine samples, and interested in methadone treatment). For the “missing positive” analyses, missing urine samples were coded as positive for opiates and cocaine. For the “missing missing” analyses, urine samples were not replaced. The study was conducted in Baltimore, MD from December 2008 to December 2012.