Figure 1.
MicroRNA miR-409-3p/-5p in the imprinted DLK1-DIO3 cluster is overexpressed in bone metastatic EMT models of human PCa. A, miR-409-3p/-5p in bone metastatic PCa models (mesenchymal cells ARCaPM compared to ARCaPE) and (LNCaPNeo verses LNCaPRANKL PCa cells). All miRNA and RNA analysis was performed by qRT-PCR analysis. B, mRNA levels of MEG9 of ARCaPE and ARCaPM PCa cells. C, miR-409-3p/-5p expression in H9 embryonic stem cells and, D, iPSCs. *: p<0.05 were considered to be statistically significant by t-test.