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Effect of AST on splenic mRNA expression of RORγt, T-bet, and Foxp3 of EAE mice. A) AST inhibited RORγt mRNA expression. B) AST increased T-bet mRNA expression. C) AST elevated Foxp3 mRNA expression. All data are presented as mean±standard error of the mean. The dose of AST used was 50 mg/kg/day. n = 5 in each group. *p < 0.05; **p < 0.01; ***p < 0.001 vs EAE group.
