Table 1.
Respiratory parameters
| ALIp | ALIexp | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| PCV | PSV | PCV | PSV | ||||||
| NS | Sigh | NS | Sigh | NS | Sigh | NS | Sigh | ||
| VT (ml) | Baseline-PEEP | 1.9 ± 0.3 | 1.9 ± 0.3 | 2.0 ± 0.2 | 2.1 ± 0.3 | 1.9 ± 0.2 | 2.0 ± 0.2 | 2.0 ± 0.2 | 2.1 ± 0.3 |
| End | 2.0 ± 0.3 | 2.1 ± 0.2 | 2.0 ± 0.3 | 2.1 ± 0.4 | 2.0 ± 0.2 | 1.9 ± 0.2 | 2.0 ± 0.2 | 2.2 ± 0.3 | |
| RR (bpm) | Baseline-PEEP | 76.3 ± 4.5 | 76.4 ± 3.7 | 65.9 ± 10.3 | 57.6 ± 11.1** | 75.8 ± 3.4 | 78.1 ± 2.3 | 60.8 ± 18.1 | 59.8 ± 17.2** |
| End | 77.3 ± 3.8 | 76.5 ± 3.7 | 63.6 ± 8.8 | 46.3 ± 11.5**# | 74.1 ± 4.3 | 78.1 ± 2.3 | 67.2 ± 14.9 | 47.3 ± 18.2**,# | |
| Ppeak,L (cmH20) | Baseline-PEEP | 13.2 ± 2.1 | 12.1 ± 0.7 | 17.1 ± 2.4 | 16.5 ± 6.5** | 10.7 ± 1.7 | 12.6 ± 0.7 | 16.0 ± 1.2* | 14.4 ± 3.8 |
| End | 13.2 ± 2.3 | 9.2 ± 0.7*,† | 14.8 ± 2.8 | 11.0 ± 1.0#† | 12.3 ± 2.7 | 10.0 ± 1.5† | 14.8 ± 1.6 | 12.4 ± 3.3† | |
| Pmean,L (cmH20) | Baseline-PEEP | 8.1 ± 0.9 | 7.7 ± 0.5 | 7.8 ± 0.7 | 7.9 ± 0.8 | 7.2 ± 0.7 | 7.9 ± 0.3 | 7.1 ± 0.8 | 7.4 ± 1.3 |
| End | 8.2 ± 1.0 | 6.6 ± 0.3*,† | 7.4 ± 0.7 | 6.2 ± 0.3#† | 7.6 ± 1.1 | 6.7 ± 0.4† | 7.2 ± 0.4 | 6.5 ± 0.9 | |
| P0.1 | Baseline-PEEP | - | - | 4.2 ± 2.7 | 4.6 ± 2.1 | - | - | 4.2 ± 1.1 | 2.2 ± 0.4 |
| End | - | - | 2.9 ± 2.2† | 1.3 ± 0.9† | - | - | 3.9 ± 0.2 | 1.3 ± 0.5†# | |
Values are mean + standard deviation (SD) of six rats in each group. †Significantly different from Baseline-PEEP (P <0.05); *significantly different from PCV-NS (P <0.05); **significantly different from PCV-Sigh (P <0.05); #significantly different from PSV-NS (P <0.05). VT, tidal volume; RR, respiratory rate; Ppeak,L, transpulmonary peak pressure; Pmean,L, transpulmonary mean pressure; P0.1, driving pressure; PEEP, positive-end expiratory pressure; NS, non-Sigh.