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. 2014 Jul 3;261(9):1794–1802. doi: 10.1007/s00415-014-7412-x

Fig. 4.

Fig. 4

Median percentage change in whole brain volume at 2 years relative to baseline and 6 months. Comparisons vs. placebo were based on analysis of covariance on ranked data, adjusted for region and normalized brain volume at 6 months. *P < 0.05 vs. placebo. BID twice daily, DMF dimethyl fumarate, TID three times daily