. 2014 Sep 7;20(33):11815–11825. doi: 10.3748/wjg.v20.i33.11815

Table 2.

Biochemical parameters in blood (mean ± SE)

Parameter	Controls (n = 14)	Patients without MHE *(n = 24) P vs* control**	Patients with mHE *(n = 16) P vs* control**	Patients with MHE Pvs without MHE	P values
cGMP in plasma (pmol/mL)	0.64 ± 0.1	6.1 ± 0.6	8.7 ± 1.1
cGMP in plasma (pmol/mL)	0.64 ± 0.1	P < 0.0001	P < 0.0001	< 0.05	< 0.0001
Nitrates + Nitrites (μmol/L)	18 ± 1	38 ± 4	44 ± 9
Nitrates + Nitrites (μmol/L)	18 ± 1	P = 0.004	P = 0.004	NS	0.001
3-Nitro-tyrosine (nmol/L)	3.5 ± 1.2	10 ± 1	43 ± 6	< 0.0001	< 0.0001
3-Nitro-tyrosine (nmol/L)	3.5 ± 1.2	10 ± 1	P < 0.0001	< 0.0001	< 0.0001
IL-6 (pg/mL)	0.7 ± 0.2	2.3 ± 0.3	4.4 ± 0.5	0.001	< 0.0001
IL-6 (pg/mL)	0.7 ± 0.2	P < 0.05	P < 0.0001		< 0.0001
IL-18 (pg/mL)	103 ± 13			< 0.05	< 0.0001
		268 ± 39	404 ± 44
		P = 0.02	P < 0.0001
Ammonia (μmol/L)	39 ± 4	84 ± 14	103 ± 33	NS	0.005
Ammonia (μmol/L)	39 ± 4	P = 0.04	P = 0.006	NS	0.005

One-way analysis of variance (ANOVA) followed by post-hoc Bonferroni’s multiple comparisons test were performed. Adjusted P values are shown. NS: Not significant.