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. Author manuscript; available in PMC: 2014 Sep 5.
Published in final edited form as: J Biomark Drug Dev. 2012 Aug 2;1(1):1000e103. doi: 10.4172/jbdd.1000e103

Figure 1.

Figure 1

Circulating miRNAs are wrapped in small membrane vesicles (microvesicles, exosomes, and apoptotic bodies), RNA-binding proteins (Ago2 and NPM1) and lipoprotein complexes (HDL and LDL complexes). In response to AMI, these miRNA carriers are released into the bloodstream.