Stability of trivalent arsenicals in a liver homogenate from a mouse exposed to iAsIII in drinking water (50 ppm As) for 9 days: liver homogenate was prepared in DIW. The direct HG-CT-AAS analysis was used to determine the concentrations of iAs (A, B), MAs (C, D) and DMAs (E, F) species in aliquots of the fresh homogenate and in aliquots stored at −80 °C (A, C, E) or 0 °C (B, D, F) for up to 22 days (mean ± SD, n = 3). To control for As recoveries during the direct analyses, iAsIII + V, MAsIII + V, and DMAsIII + V were determined in aliquots of the fresh homogenate digested in phosphoric acid (mean, n = 3). *The concentration is significantly different from that found in the fresh homogenate (p < 0.01).