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. Author manuscript; available in PMC: 2014 Sep 5.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 Apr 26;32(7):1724–1731. doi: 10.1161/ATVBAHA.112.250464

Figure 4.

Figure 4

Platelets adhere to the RGD motif presented as part of an extended cadherin 6 (Cdh6) sequence. Platelets from healthy human donors (A) and wild-type mice (B) adhered to glass slides coated with a peptide corresponding to Cdh6 amino acids 73–95, containing the Cdh6 RGD motif. Mutating the RGD to RGE abrogated platelet adhesion. RGD indicates arginine-glycine-aspartic acid.