Serum glucose (A), insulin (B) concentrations and HOMA-IR (C) in DM (solid cycle), HFD (open triangle), and CON (open cycle) rats after oral glucose loading. Data were expressed as mean±SD of 6 rats, bP<0.05, cP<0.01 vs CON rats. eP<0.05, fP<0.01 vs HFD rats.