Figure 5.
Effect of curcumin (Cur) on STAT3 acetylation and Ang II-induced STAT3 phosphorylation in NRK-52E cells. After a 1 h treatment with Ang II (1 μmol/L) with or without a 1 h Cur (12.5 μmol/L) pretreatment, acetyl-STAT3 (Lys685) (A) and phospho-STAT3 (Tyr705) (B) were analyzed by Western blot analysis. Data are presented as the mean±SEM of 3–4 experiments. bP<0.05, cP<0.01 compared with control [Ang II (−) and Cur (−)]. fP<0.01 compared with Ang II only.