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TA3-induced cholestasis and disrupted bile acids homeostasis in SD rats. (A) Changes in total BA levels in serum after TA3 administration at 100 mg/kg daily for 14 d. (B) The determination of 8 types of BA components (CA, TCA, GCA, GCDCA, CDCA, TCDCA, TDCA, and DCA) in bile. The data are presented as the mean±SD (n=4–6). bP<0.05, cP<0.01 vs vehicle.
