Figure 7.

Effects of NAC on d8-TCA uptake and efflux in TA3-treated SCRH. Cells were incubated with d8-TCA (1 μmol/L) after treatment with TA3+NAC for 2 h (A) and 24 h (B), and d8-TCA accumulation was determined. D8-TCA efflux capacity was calculated as the BEI of d8-TCA. (C) BEI of d8-TCA after treatment for 2 h. (D) BEI of d8-TCA after treatment for 24 h. The data are presented as the mean±SD (n=3). ^bP<0.05, ^cP<0.01 vs vehicle. ^eP<0.05, ^fP<0.01 (TA3+NAC treatment vs TA3 alone).