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. Author manuscript; available in PMC: 2014 Sep 5.
Published in final edited form as: Chem Rev. 2013 Jun 17;113(8):5701–5765. doi: 10.1021/cr4000144

Scheme 149.

Scheme 149

a) Wittig Olefination of 1-Aza-2-adamantanone by Kirby; b) Petasis Olefination of Medium Bridged Twisted Lactams by Aubé; c) Wittig Olefination of Tröger’s Base-Derived Twisted Lactams by Wärnmark