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. Author manuscript; available in PMC: 2014 Sep 5.
Published in final edited form as: Chem Rev. 2013 Jun 17;113(8):5701–5765. doi: 10.1021/cr4000144

Table 1.

Synthesis of 1-Azabicyclo[5.2.1]decan-9-one via Rh-Catalyzed C–H Insertion by Doyle

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entry n 144 Rh2L4 ratio of
145:146		 combined
yield (%)		 ee of
145 (%)		 ee of
146 (%)
1 0 144a Rh2(5S-MEPY)4 1:99 67 n/a 97
2 1 144b Rh2(4S-MEOX)4 74:26 95 98 15
3 1 144b Rh2(5S-MEPY)4 33:67 67 97 30
4 1 144b Rh2(4S-MACIM)4 61:39 81 96 66
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