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. Author manuscript; available in PMC: 2014 Sep 5.

Published in final edited form as: Diabetologia. 2013 Dec 4;57(3):603–613. doi: 10.1007/s00125-013-3128-1

Table 1.

Characteristic of the MMP9 null mice during the hyperinsulinemic-euglycemic clamp.

		CHOW				HF
		Female		Male		Female		Male
		mmp9^+/+	mmp9^−/−	mmp9^+/+	mmp9^−/−	mmp9^+/+	mmp9^−/−	mmp9^+/+	mmp9^−/−
N		4	5	6	6	6	6	6	6
Weight (g)		23±0.2	21±0.6	28±0.7	26±0.9	33±1.5	30±1.0	40±1.7	40±1.3
Blood Glucose (mmol/l)	Basal	6.8±0.4	6.3±0.1	7.3±0.1	6.7±0.4	7.0±0.6	7.2±0.3	6.8±0.4	8.2±0.6
Blood Glucose (mmol/l)	Clamp^a	8.2±0.2	8.3±0.2	8.5±0.1	8.4±0.2	8.4±0.1	8.7±0.2	8.4±0.1	8.2±0.1
Plasma Insulin (pmol/l)	Basal	86±17	189±52	258±52	224±17	344±69	430±69	1136±310	809±103
Plasma Insulin (pmol/l)	Clamp^a	568±34	757±34^*	1084±69	1015±86	1325±172	1119±86	2805±396	2255±344
Plasma NEFA (mmol/l)	Basal	0.64±0.06	0.61±0.09	0.68±0.05	0.65±0.07	0.53±0.10	0.61±0.04	0.56±0.04	0.51±0.09
Plasma NEFA (mmol/l)	Clamp^a	0.14±0.02	0.11±0.04	0.20±0.05	0.18±0.02	0.20±0.04	0.25±0.06	0.22±0.03	0.24±0.03

^a

Data are presented as the average of values obtained from 80–120min of the IC_v.

^*

p<0.05 Compared to Chow-fed female mmp9^+/+.

All data are expressed as mean ± SEM.