FIG. 4.

Mean densities (error bars, SE) of VRE for groups of mice in communal cages. A mouse with high-density VRE stool colonization (∼7 log₁₀ CFU/g) was placed in a cage along with four mice with no previous exposure to VRE. All mice were treated with subcutaneous clindamycin (1.4 mg) once daily from day 0 to day 5. The control cage received regular drinking water (•), and the experimental cage received ramoplanin in drinking water (□) from days 0 to 9 (solid line). On day 9 all mice were placed in individual cages and ramoplanin was discontinued.