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Global cellular HDAC activity is suppressed by apicidin but not by PTH. Overall relative HDAC activities were determined in UMR106 cells. Cells were treated with solvent control (-), 1 μm PTH, or 10 μm apicidin for 1 h before measuring total HDAC activities using a luciferase reporter kit. Shown are mean ± S.E. of a representative experiment.
