TABLE 3.
Fluoroquinolone activity against gram-negative respiratory tract pathogens from the Asia-Pacific region, 1999 to 2001
Organism | No. of strains | Antibiotic | MIC50a (μg/ml) | MIC90 (μg/ml) | % Susceptible at concn (μg/ml) of:
|
||||
---|---|---|---|---|---|---|---|---|---|
0.06 | 0.12 | 0.25 | 0.5 | 1 | |||||
H. influenzae | 1,341 | Garenoxacin | ≤0.03 | ≤0.03 | 99 | 99 | 99 | 99 | 99 |
1,341 | Ciprofloxacin | ≤0.03 | ≤0.25 | 84 | 85 | 99 | 99 | 99 | |
1,341 | Levofloxacin | ≤0.03 | ≤0.03 | 99 | 99 | 99 | 99 | 99 | |
1,341 | Gatifloxacin | ≤0.03 | ≤0.03 | 99 | 99 | 99 | 99 | 99 | |
819 | Moxifloxacin | ≤0.03 | ≤0.03 | 99 | 99 | 99 | 100 | 100 | |
745 | Gemifloxacin | ≤0.008 | ≤0.03 | 99 | 99 | 99 | 99 | 99 | |
M. catarrhalis | 600 | Garenoxacin | 0.03 | 0.03 | 99 | 99 | 99 | 100 | 100 |
600 | Ciprofloxacin | 0.03 | ≤0.25 | 89 | 89 | 99 | 99 | 100 | |
600 | Levofloxacin | ≤0.03 | 0.06 | 99 | 99 | 99 | 99 | 100 | |
600 | Gatifloxacin | ≤0.03 | ≤0.03 | 99 | 99 | 99 | 100 | 100 | |
372 | Moxifloxacin | 0.06 | 0.06 | 99 | 99 | 99 | 99 | 100 | |
284 | Gemifloxacin | ≤0.008 | ≤0.03 | 99 | 100 | 100 | 100 | 100 |
MIC50, MIC at which 50% of the isolates tested are inhibited.