Figure 2.

TLR2 KO previously inoculated with LVS clpB survive a lethal LVS challenge. B6 or TLR2 KO mice were intranasally inoculated with 5 × 10⁴ CFU LVS clpB or were left naive. Thirty-five days later, mice were intranasally challenged with 5 × 10³ CFU LVS and (A) survival was determined. (B) Mice were weighed daily and weight loss is reported as a percentage of starting weight. Data are combined from two independent experiments. n = 6–10 mice/group.