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In vitro activities of conventional AMB and its lipid formulations against Coccidioides spp.
| Compound | MIC (μg/ml) at 48 h
|
MLC (μg/ml) at 48 h
|
||
|---|---|---|---|---|
| Strain 98-1037 | Strain 98-293 | Strain 98-1037 | Strain 98-293 | |
| AMB lipid complex | 0.125 | 0.25 | 0.5 | 2 |
| AMB colloidal dispersion | 0.06 | 0.125 | 0.5 | 2 |
| Liposomal AMB | 0.5 | 1 | 1 | 4 |
| AMB | 0.25 | 0.5 | 0.25 | 0.5 |
