TABLE II. Levels of antimony (Sb) in the whole blood and plasma of male rats 105 days after the end of a 21-days course of treatment with the vehicle-only (controls) or meglumine antimoniate (MA)a .
| Treatment | Vehicle-only (1.76 mL/kg body wt/d, s.c. x 21 d) (ng/g) | MA (300 mg SbV/kg body wt/d, s.c. x 21 d) (ng/g) |
|---|---|---|
| Whole blood | 3 ± 0 | 35,614 ± 4,625 |
| Plasma | < LOQb | 21 ± 12 |
a: 300 mg SbV/kg body wt/d, subcutaneous (s.c.); b: levels below the limit of quantification (LOQ) of the method (1.7 ng Sb/g). Data are shown as the means ± standard deviation of Sb concentrations (wet wt) determined by inductively coupled plasma-mass spectrometry. Vehicle-only group, n = 6; MA-treated group, n = 6.