TABLE II. Description of 31 Candida albicans and 17 Candida glabrata isolates comprising gender and age of patients, date of isolation, clinical sample, antifungal agents minimal inhibitory concentration (MIC) values and results of random amplified polymorphic DNA polymerase chain reaction (RAPD) analysis.
| Isolate code | Patient code | Gender | Age | Date of isolation | Clinical sample | MIC values (mg/L)
|
RAPD profile | RAPD cluster | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| AMB | FLC | 5FC | VRC | ||||||||
| CA1 | SE | F | 78 | 12 Jan 2011 | ETA | 1 | 4 | ≤ 1 | ≤ 0.12 | A | A |
| CA2 | DM | M | 25 | 16 Mar 2011 | ETA | 1 | ≤ 1 | ≤ 1 | ≤ 0.12 | U1 | U |
| CA3 | WM | M | 80 | 30 May 2011 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | R | R |
| CA4 | BL | M | 53 | 07 Jun 2011 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | D | D |
| CA5 | PA | M | 50 | 18 Aug 2011 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | N | N |
| CA6 | LP | M | 28 | 05 Sep 2011 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | K1 | K |
| CA7 | KL | M | 28 | 21 Sep 2011 | Urine | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | O1 | O |
| CA8 | PB | F | 43 | 22 Sep 2011 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | O2 | O |
| CA9 | SR | M | 38 | 05 Oct 2011 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | K2 | K |
| CA10 | SL | M | 90 | 07 Oct 2011 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | L | L |
| CA11 | BM | F | 66 | 15 Nov 2011 | ETA | 1 | ≤ 1 | ≤ 1 | ≤ 0.12 | P | P |
| CA12 | BM | F | 66 | 16 Nov 2011 | Urine | 1 | ≤ 1 | ≤ 1 | ≤ 0.12 | M1 | M |
| CA13 | LF | M | 90 | 29 Dec 2011 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | M2 | M |
| CA14 | WH | M | 34 | 03 Jan 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | C | C |
| CA15 | BuM | F | 53 | 12 Jan 2012 | ETA | 1 | ≤ 1 | ≤ 1 | ≤ 0.12 | E1 | E |
| CA16 | PZ | M | 87 | 09 Mar 2012 | ETA | 1 | ≤ 1 | ≤ 1 | ≤ 0.12 | T1 | T |
| CA17 | ZW | M | 83 | 04 Apr 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | E2 | E |
| CA18 | KT | M | 61 | 04 Apr 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | F | F |
| CA19 | NA | F | 61 | 16 Apr 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | E4 | E |
| CA20 | ZJ | F | 68 | 08 Oct 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | J1 | J |
| CA21 | OJ | M | 69 | 08 Oct 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | T2 | T |
| CA22 | PP | M | 19 | 10 Oct 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | E3 | E |
| CA23 | NN | F | 41 | 12 Oct 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | J2 | J |
| CA24 | OA | F | 45 | 17 Oct 2012 | ETA | ≤ 0.25 | ≤ 1 | ≤ 1 | ≤ 0.12 | G | G |
| CA25 | MR | M | 86 | 12 Nov 2012 | ETA | ≤ 0.25 | 4 | ≤ 1 | ≤ 0.12 | U2 | U |
| CA26 | TP | M | 57 | 26 Nov 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | H1 | H |
| CA27 | ZaJ | F | 79 | 28 Nov 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | H2 | H |
| CA28 | ZS | F | 94 | 28 Nov 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | S | S |
| CA29 | KM | F | 76 | 18 Dec 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | I1 | I |
| CA30 | CM | F | 69 | 24 Dec 2012 | ETA | ≤ 0.25 | ≤ 1 | ≤ 1 | ≤ 0.12 | B | B |
| CA31 | KH | F | 62 | 28 Dec 2012 | ETA | 0.5 | ≤ 1 | ≤ 1 | ≤ 0.12 | I2 | I |
| CG1 | SZ | F | 80 | 28 Apr 2011 | ETA | ≤ 0.25 | 8 | ≤ 1 | ≤ 0.12 | a | a |
| CG2 | WM | M | 80 | 30 May 2011 | ETA | 0.5 | 4 | ≤ 1 | 0.25 | f1 | f |
| CG3 | PJ | M | 80 | 15 Jun 2011 | ETA | 1 | 8 | ≤ 1 | ≤ 0.12 | g1 | g |
| CG4 | WJ | F | 47 | 29 Jun 2011 | ETA | 0.5 | 8 | ≤ 1 | ≤ 0.12 | h | h |
| CG5 | CA | M | 57 | 16 Sep 2011 | ETA | 1 | 8 | ≤ 1 | ≤ 0.12 | g2 | g |
| CG6 | SL | M | 90 | 07 Oct 2011 | ETA | 1 | 4 | ≤ 1 | ≤ 0.12 | i | i |
| CG7 | SJ | M | 70 | 28 Oct 2011 | ETA | 0.5 | 32 | ≤ 1 | ≤ 0.12 | f2 | f |
| CG8 | WE | F | 37 | 31 Jan 2012 | ETA | 1 | 8 | ≤ 1 | 1 | e2 | e |
| CG9 | PZ | M | 87 | 04 Apr 2012 | ETA | 0.5 | 4 | ≤ 1 | 0.25 | d1 | d |
| CG10 | LG | F | 72 | 18 Apr 2012 | ETA | 1 | 4 | ≤ 1 | ≤ 0.12 | d1 | d |
| CG11 | JJ | M | 57 | 07 Aug 2012 | ETA | 0.5 | 4 | ≤ 1 | ≤ 0.12 | e1 | e |
| CG12 | BG | F | 77 | 08 Aug 2012 | ETA | 0.5 | 8 | ≤ 1 | ≤ 0.12 | c | c |
| CG13 | ZJ | F | 68 | 04 Oct 2012 | ETA | 0.5 | 2 | ≤ 1 | ≤ 0.12 | d3 | d |
| CG14 | OJ | M | 69 | 05 Oct 2012 | ETA | 1 | 2 | ≤ 1 | ≤ 0.12 | d2 | d |
| CG15 | GG | F | 78 | 25 Oct 2012 | ETA | ≤ 0.25 | 2 | ≤ 1 | ≤ 0.12 | d4 | d |
| CG16 | GH | F | 87 | 18 Dec 2012 | ETA | 0.5 | 2 | ≤ 1 | ≤ 0.12 | j | j |
| CG17 | CM | F | 69 | 24 Dec 2012 | ETA | 0.5 | 8 | ≤ 1 | ≤ 0.12 | b | b |
AMB: amphotericin B; CA1-CA31: C. albicans strains; CG1-CG17: C. glabrata strains; ETA: endotracheal aspirate; F: female; FLC: fluconazole; M: male; VRC: voriconazole; 5FC: 5-fluorocytosine.