Table IV. Complete univariate logistic regression for linear growth impairment at last follow-up visit.
| Factor | Comparison group | Reference group | OR | CI | P value | Overall P value |
|---|---|---|---|---|---|---|
| Sex | Female | Male | 0.82 | (0.59, 1.14) | .2342 | .2342 |
| Race | Black | White | 1.27 | (0.79, 2.02) | .3213 | .0009 |
| Hispanic | 1.79 | (1.11, 2.90) | .0172 | |||
| Other | 2.60 | (1.57, 4.29) | .0002 | |||
| Primary diagnosis | Other cholestatic | Biliary atresia | 3.84 | (2.42, 6.11) | <.0001 | <.0001 |
| Fulminant liver failure | 0.38 | (0.18, 0.80) | .0105 | |||
| Metabolic disease | 1.68 | (1.03, 2.73) | .0359 | |||
| Cirrhosis | 1.45 | (0.73, 2.88) | .2929 | |||
| Other | 0.84 | (0.42,1.66) | .6072 | |||
| Era of transplant | ≥2002 | 1995-2001 | 1.13 | (0.81, 1.58) | .4558 | .4558 |
| Age at transplant | <6 mo | 13+ y | 0.42 | (0.14, 1.28) | .1287 | .2118 |
| 6-11 mo | 0.89 | (0.47, 1.68) | .7224 | |||
| 1-4 y | 0.69 | (0.41, 1.19) | .1828 | |||
| 5-12 y | 1.05 | (0.65, 1.68) | .8499 | |||
| Donor type | Live | Cadaveric whole | 0.77 | (0.46, 1.28) | .3153 | .1709 |
| Cadaveric reduced | 0.60 | (0.36, 1.00) | .0505 | |||
| Cadaveric split | 0.68 | (0.34, 1.33) | .2552 | |||
| Patient status at transplant | ICU | Not hospitalized | 0.59 | (0.38, 0.92) | .0209 | .0488 |
| Hospitalized, not in ICU | 0.73 | (0.44, 1.21) | .2198 | |||
| Nutrition intake at listing | Intravenous | Oral | 0.72 | (0.39, 1.34) | .2999 | .0102 |
| Enteral | 1.87 | (1.18, 2.96) | .0072 | |||
| Height failure at transplant | Yes | No | 7.72 | (5.17, 11.52) | <.0001 | <.0001 |
| Immunosuppression at transplant | Cyclosporin base | Tacrolimus base | 1.02 | (0.68, 1.54) | .9178 | .7735 |
| Other | 0.77 | (0.37, 1.61) | .4908 | |||
| Education prior to transplant | Part time | Full time | 1.36 | (0.61, 3.01) | .4535 | .3590 |
| Home schooling | 1.57 | (0.72, 3.39) | .2563 | |||
| No education | 1.74 | (0.77, 3.97) | .1849 | |||
| Not of school age | 0.85 | (0.59, 1.23) | .3921 | |||
| In college/completed HS/GED | 0.00 | (0.00, 1) | .9857 | |||
| Special education prior to transplant | Yes | No | 2.69 | (1.49, 4.86) | .0011 | .0031 |
| No education | 1.06 | (0.73, 1.53) | .7661 | |||
| Prednisone use up to 12 mo | #6 mo | No | 0.51 | (0.20, 1.32) | .1656 | .2894 |
| >6 mo | 0.65 | (0.27, 1.59) | .3458 | |||
| CMV before last height measurement | Yes | No | 1.09 | (0.66, 1.83) | .7293 | .7293 |
| EBV before last height measurement | Yes | No | 1.03 | (0.56, 1.91) | .9129 | .9129 |
| PTLD before last height measurement | Yes | No | 1.09 | (0.40, 2.96) | .8680 | .8680 |
| Re-transplanted | Yes | No | 2.35 | (1.43, 3.87) | .0008 | .0008 |
| CNI level at last height measurement | Low | Very low | 0.71 | (0.44, 1.13) | .1510 | .1045 |
| Medium | 0.82 | (0.48, 1.41) | .4671 | |||
| High | 1.36 | (0.73, 2.52) | .3295 | |||
| Tanner stage at last height measurement | 1 | 5 | 1.85 | (0.77, 4.43) | .1696 | .5055 |
| 2 | 1.67 | (0.61, 4.54) | .3178 | |||
| 3 | 2.25 | (0.79, 6.38) | .1274 | |||
| 4 | 1.22 | (0.44, 3.37) | .7009 | |||
| Steroids at transplant | Yes | No | 1.81 | (1.24, 2.64) | .0022 | .0022 |
| Total bilirubin at transplant (mg/dL) | Continuous | 0.997 | (0.981, 1.014) | - | .7461 | |
| Total bilirubin at 12 mo (mg/dL) | Continuous | 1.003 | (0.964, 1.045) | - | .8695 | |
| Total bilirubin at last height measurement (mg/dL) | Continuous | 1.027 | (0.958, 1.101) | - | .4555 | |
| Albumin at transplant (g/dL) | Continuous | 1.10 | (0.88, 1.37) | - | .4129 | |
| Albumin at 12 mo (g/dL) | Continuous | 0.70 | (0.50, 0.98) | - | .0392 | |
| Albumin at last height measurement (g/dL) | Continuous | 0.72 | (0.50, 1.03) | - | .0726 | |
| Log(INR) at transplant | Continuous | 0.59 | (0.39, 0.89) | - | .0126 | |
| Log(INR) at 12 mo | Continuous | 3.75 | (0.43, 33.04) | - | .2341 | |
| Log(INR) at last height measurement | Continuous | 2.29 | (0.72, 7.29) | - | .1594 | |
| GGT at 12 mo (U/L) | Continuous | 1.001 | 1.000, 1.002 | - | .0031 | |
| GGT at last height measurement (U/L) | Continuous | 1.001 | (1.000, 1.002) | - | .1272 | |
HS/GED, high school/general educational development.
Bold values indicate significant < .05.