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. 2014 Jul 9;289(34):23701–23711. doi: 10.1074/jbc.M114.576272

FIGURE 1.

FIGURE 1.

Cell adherence induced by alanine-substituted RasGAP317–326 peptides. A and B, U2OS cells were cultured overnight and then treated for 8 h with 20 μm TAT or 20 μm of the indicated TAT-coupled peptides or left untreated. The cells were then subjected to trypsin-mediated detachment assays. The images shown in panel A correspond to 20 μm peptide-treated cells (n = 4 independent experiments). Scale bar: 200 μm for all images. w/o trypsin, without trypsin. B, dose-response quantitation (n = 4 independent experiments). C, alignment of the p120 RasGAP317–326 sequences from different species. The amino acids conserved during evolution are shaded in gray. Drosoph., Drosophila.

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