Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Residues important for interaction of pyrin PYD with ASC PYD localize to three clusters. A, ribbon representation of the pyrin PYD structure highlighting residues that affect interaction when mutated. Basic, acidic, and hydrophobic residues are colored blue, red, and green, respectively. Clusters of residues that form an interaction site are circled. B, surface electrostatic potential of pyrin PYD shown in the same orientation as in A and indicating residues important for interaction.
