FIGURE 1.

TbBILBO1 domain organization and sequence alignment. A, schematic depicting the arrangement of the four domains of TbBILBO1: NTD, EF, CCD, and LZ. Amino acid numbers are indicated above the schematic. B, sequence alignment of TbBILBO1 and homologs from related trypanosomatids. Identical (black) and similar (gray) residues are shaded. Domains are indicated by bars under the aligned sequences using the color scheme detailed at the bottom. Conserved leucines in the C-terminal LZ are highlighted in gold. Tb, T. brucei; Tc, T. cruzi; Lb, Leishmania braziliensis; Li, Leishmania infantum; Lm, Leishmania major.