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Agonist stimulation of mutant M1 mAChR-mediated [Ca2+]i mobilization. Shown are data for the wild-type (A), F772.56I (B), Y822.61A (C), Y852.64A (D), W1013.28A (E), I180A (F), and L183A (G) mutants. Data represent the mean ± S.E. of at least three experiments performed in duplicate. The error bars not shown lie within the dimensions of the symbol.
