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. 2014 Jul 8;289(34):23609–23628. doi: 10.1074/jbc.M114.561829

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© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 9. — ALG-2/Sec31-PRR inhibits transport independently of known interactions with Sec16, Sec23, or Sar1. A, as in Fig. 5A but employing FLAG-Sec31-PRR residues 800–1113 (PRR) or the indicated PRR construct mutants. B, as in A but employing PRR deletion constructs as indicated rather than point mutations. Asterisks, p values for two-tailed t tests for the indicated value versus the 12-min mock control; *, p < 0.05; **, p < 0.01. Shown are averages of three independent replicates of each experiment. Each bar represents ≥90 cells. Error bars, S.E.