TABLE 2.
Baseline characteristics of ITT population
| Characteristic | Value for anidulafungin dose group (mg)a
|
||
|---|---|---|---|
| 50 | 75 | 100 | |
| Age [median yr (range)] | 52 (18-88) | 54 (21-87) | 59 (26-88) |
| Sex | |||
| Male [n (%)] | 13 (33) | 21 (53) | 18 (45) |
| Female [n (%)] | 27 (68) | 19 (48) | 22 (55) |
| Wt (median [kg]) | 68.9 | 76.1 | 70.6 |
| APACHE II score (mean ± SD) | 13.4 ± 8.3 | 18.6 ± 9.7 | 15.0 ± 8.2 |
| APACHE II score ≥20 [n (%)] | 7 (18) | 12 (30) | 10 (25) |
| Absolute neutrophil count of <500 [n (%)] | 7 (18) | 5 (13) | 4 (10) |
| Diabetes mellitus [n (%)] | 13 (33) | 12 (30) | 11 (28) |
| Prior systemic antifungal treat- ment [n (%)] | 23 (58) | 28 (70) | 31 (78) |
a
Forty patients per group.