Table II.
p85 expression and breast cancer subtypes.
| PI3K expression | ||||
|---|---|---|---|---|
|
|
||||
| Parameter | Negtive, (n=76) | Moderately positive (n=28) | Strongly positive (n=22) | P-valuea |
| ER/PR-positive, n (%) | 50 (72.5) | 13 (18.8) | 6 (8.7) | 0.008b |
| HER2-positive, n (%) | 14 (56.0) | 6 (24.0) | 5 (20.0) | |
| Triple-negative, n (%) | 12 (37.5) | 9 (28.1) | 11 (34.4) | |
a
P-values were derived from a comparison between negative, moderately positive and strongly positive subtypes;
b
obtained using the χ2 test.
PI3K, phosphatidylinositol 3-kinase. ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.