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. 2004 Jun;48(6):2101–2107. doi: 10.1128/AAC.48.6.2101-2107.2004

TABLE 3.

Susceptibilities to fluoroquinolones of pneumococcal isolates from 12 Asian countriesa

Country Levofloxacin
Moxifloxacin
Gatifloxacin
Ciprofloxacin
MIC (mg/liter)
% I % R MIC (mg/liter)
% I % R MIC (mg/liter)
% I % R MIC (mg/liter)
% R
90% Range 90% Range 90% Range 90% Range
Korea 2 0.25-2 0.0 0.0 0.25 0.06-0.5 0.0 0.0 0.5 0.12-1 0.0 0.0 2 0.25-4 6.5
China 1 0.12-2 0.0 0.0 0.25 0.004-1 0.0 0.0 0.5 <0.03-1 0.0 0.0 2 0.12->32 3.6
Thailand 1 0.5-2 0.0 0.0 0.25 0.03-0.5 0.0 0.0 0.5 <0.03-1 0.0 0.0 2 0.5-8 3.8
Taiwan 1 0.5-2 0.0 1.8 0.25 0.03-0.5 1.8 0.0 0.5 0.03-1 1.8 1.8 2 0.5-8 7
India 1 0.06-8 0.0 1.3 0.25 0.015-2 1.3 0.0 0.5 <0.03-8 0.0 1.4 2 0.12-16 4
Sri Lanka 1 0.5-2 0.0 0.0 0.25 0.06-0.5 0.0 0.0 0.5 0.12-1 0.0 0.0 2 0.5-4 9.5
Singapore 1 0.12-4 2.9 0.0 0.12 0.015-0.25 0.0 0.0 0.5 0.06-1 0.0 0.0 2 0.5-16 5.9
Malaysia 1 0.015-2 0.0 0.0 0.25 <0.002-1 0.0 0.0 0.5 0.06-1 0.0 0.0 2 <0.015-4 4.6
Vietnam 1 0.25-1 0.0 0.0 0.25 0.06-0.25 0.0 0.0 0.5 0.06-1 0.0 0.0 2 0.12->4 4.8
Philippines 1 0.5-2 0.0 0.0 0.25 0.03-0.5 0.0 0.0 0.5 0.06-1 0.0 0.0 2 0.5-4 9.1
Saudi Arabia 1 <0.004-2 0.0 0.0 0.25 <0.002-0.25 0.0 0.0 0.5 0.015-1 0.0 0.0 2 <0.015-4 2.6
Hong Kong 2 0.015-32 0.0 8.0 0.5 0.015-4 6.3 1.8 1 0.03-8 0.9 8.3 4 0.015-32 11.8
    Total 1 <0.004-32 0.1 1.6 0.25 <0.002-4 1.3 0.3 0.5 0.03-8 0.3 1.6 2 0.008->32 6
a

MIC breakpoints for individual fluoroquinolones are as follows: for levofloxacin, I = 4 mg/liter and R = 8 mg/liter; for moxifloxacin, I = 2 mg/liter and R = 4 mg/liter; for gatifloxacin, I = 2 mg/liter and R ≥ 4 mg/liter; and for ciprofloxacin R ≥ 4 mg/liter.