FIG. 1.

Fluoroquinolone treatment of rabbit eyes infected with ofloxacin-sensitive S. aureus strains. Rabbit corneas were infected with ofloxacin-sensitive S. aureus and treated with moxifloxacin (0.5%), levofloxacin (0.5%), or ciprofloxacin (0.3%). Rabbit eyes were treated every hour from 4 to 9 (A and B) or from 10 to 15 (C and D) h p.i. Following sacrifice of the rabbits, the numbers of viable S. aureus organisms per cornea was quantified and expressed as base 10 logarithms ± standard deviations (indicated by error bars). The number of eyes per group (n) was 6 unless specified by one of the following labels above the error bars: (a), n = 12; (b), n = 15; (c), n = 22; (d), n = 10; (e), n = 18.