Table I.

Correlation between NEK2, Mcm7 and Ki67 expression and the clinicopathological features of NSCLC.

	Total		NEK2			Mcm7			Ki67
Characteristics	n	%	Positive case	%	P-value	Positive case	%	P-value	Positive case	%	P-value
Age
≤60	112	41.5	25	35.7	0.255	33	34.7	0.097	23	34.8	0.208
>60	158	58.5	45	64.3		62	65.3		43	65.2
Gender
Female	78	28.9	47	67.1	0.395	29	30.5	0.662	24	36.4	0.123
Male	192	71.1	23	32.9		66	69.5		42	63.6
Histological type
SCC	162	60.0	42	60.0	1.000	57	60.0	1.000	45	68.2	0.119
ADC	108	40.0	28	40.0		38	40.0		21	31.8
Differentiation
Well	59	21.9	14	20.0	0.277	23	24.2	0.729	16	24.2	0.600
Moderate	86	31.9	18	25.7		28	29.5		23	34.8
Poor	125	46.3	38	54.3		44	46.3		27	40.9
Tumor size
T1	78	28.9	10	14.3	0.000a	19	20.0	0.017a	19	28.8	0.156
T2	143	53.0	37	52.9		52	54.7		30	45.5
T3–4	49	18.1	23	32.9		24	25.3		17	25.8
Lymph node metastasis
Negative	143	53.0	27	38.6	0.011a	42	44.2	0.057	31	47.0	0.053
N1-positive	72	26.7	27	38.6		33	34.7		25	37.9
N2–3-positive	55	20.4	16	22.9		20	21.1		10	15.2
Metastasis
M0	265	98.1	68	97.1	0.469	91	95.8	0.034a	63	95.5	0.062
M1	5	1.9	2	2.9		4	4.2		3	4.5

^aSignificantly different.

NEK2, never in mitosis gene A (NIMA)-related kinase 2; mcm7, minichromosome maintenance complex component 7; NSCLC, non-small cell lung cancer; SSC, squamous cell carcinoma; ADC, adenocarcinoma.