Table I.
Case | Author (ref.) | Age, years | Tumor diameter, cm | Tumor stage | Clinical manifestation | Growth pattern | Histological type of SCC | Immumohistochemical staining of OGC | Treatment | Follow-up/Status |
---|---|---|---|---|---|---|---|---|---|---|
1 | Pang (7) | 65 | 6 | Ib | IVB | Polypoid mass | Sarcomatoid type | Positive for Kp1 and CD68; negative for CK and vimentin | Hysterectomy and lymphadenectomy; radiotherapy and chemotherapy | 7 weeks, DOD |
2 | Pang (7) | 61 | 5 | Ib | IVB | Polypoid mass | Sarcomatoid type | Positive for Kp1 and CD68; negative for CK and vimentin | Hysterectomy and lymphadenectomy; radiotherapy and chemotherapy | 14 months, DOD |
3 | Singh et al (8) | 60 | 4.5 | Ib | IVB | Infiltrated mass | NK type | Positive for CD68; negative for CK, EMA and vimentin | Radiotherapy and chemotherapy | 6 months, ACR |
4 | Present case | 84 | 5 | Ib | IVB | Polypoid mass | NK type | Positive for CD68 and vimentin; negative for CK | Radiotherapy | 8 months, DOD |
Tumor stage was diagnosed in accordance with the International Federation of Gynecology and Obstetrics staging for staging for carcinoma of the vulva, cervix, and endometrium (2009) (12). OGCs, osteoclast-like giant cells; IVB, irregular vaginal bleeding; SCC, squamous cell carcinoma; NK, non-keratinizing; DOD, dead of disease; ACR, alive with complete regression of the growth.