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. 2014 Jul 31;8(4):1849–1855. doi: 10.3892/ol.2014.2401

Figure 3.

Figure 3

(A) Tubular network structures (VM) were formed by U251 cells on Matrigel (x40 magnification). The CCM inhibited the VM formation of the U251 cells in a dose-dependent manner (x40 magnification). At 20 μM, CCM markedly inhibited the formation of the VM structure by the U251 cells; these levels were significantly different compared with the control group (P<0.05). At 40 μM curcumin, the tubular network structures on the Matrigel were disrupted almost completely (P<0.05). (B) The number of VM structures in every group were quantified. Three independent experiments were performed. Values are expressed as the mean ± standard deviation. *P<0.05 vs. control group. VM, vasculogenic mimicry; CCM, curcumin; DMSO, dimethyl sulfoxide.