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mRNA expression levels of EphA2, PI3K and MMP-2 following CCM treatment, examined by quantitative PCR. GAPDH served as an internal reference. The CCM suppressed the mRNA expression level of (A) EphA2, (B) PI3K and (C) MMP-2 in a dose-dependent manner. Three independent experiments were performed. Values are expressed as the mean ± standard deviation. *P<0.05 vs. control group. CCM, curcumin; DMSO, dimethyl sulfoxide.
