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Association between Topo II-α protein expression and Topo II-α amplification in 48 patients with laryngeal squamous cell carcinoma.
| FISH | |||
|---|---|---|---|
|
|
|||
| IHC | Patents, n | Non-amplification | Amplification |
| (−) | 15 | 14 | 1 |
| (+) | 12 | 11 | 1 |
| (++) | 17 | 12 | 5 |
| (+++) | 4 | 4 | 0 |
IHC, immunohistochemistry; FISH, fluorescence in situ hybridization.
