A simplified schematic of fear neurocircuitry, showing functional homology of rat
and human brain regions. PL in rat and dACC in human are homologues, both
project to the lateral nucleus of the amygdala. IL in rat and vmPFC in human are
homologues, both project to the basal nucleus and to intercalated cells of the
amygdala. The circuitry within the amygdala is shared among species. Arrowheads
represent excitatory projections and circle-endings represent inhibitory
projections. Within the amygdala, green shapes represent glutamatergic
(excitatory) cells and red shapes represent GABAergic (inhibitory) cells.
Projections from lateral nucleus to CeL, from basal nucleus to CeM, and some
other connections are not shown.
FIGURE ABBREVIATIONS:
CeL = centrolateral subdivision; CeM = centromedial subdivision; dACC = dorsal
anterior cingulate cortex; H = hippocampus; IL = infralimbic cortex; ITC =
intercalated neurons; PL = prelimbic cortex; SC = somatosensory cortex; T =
thalamus