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. 2014 Sep 5;9(9):e106183. doi: 10.1371/journal.pone.0106183

Table 1. Study characteristics from published studies on the relation of the TNF-α-308G/A polymorphism to OSAS risk in this meta-analysis.

Author	Year	Country	Ethnicity	Cases	Controls	Male (%)		Age, Mean(SD) [Range], y		BMI(kg/m²)		Source of control	Controls matched for	Methods
						Cases	Controls	Cases	Controls	Cases	Controls
Popko et al ²⁷	2008	Poland	European	102	77	72.6	50.7	[21.0–77.0]	[17.0–65.0]	NA	NA	Population based	BMI	PCR-RFLP
Khalyfa et al ²⁵	2011	United States	mixed	138	151	50	50	(7.2±0.2)	(7.2±0.3)	NA	NA	Population based	age, sex, ethnicity and BMI	TaqMan
Riha et al ³⁰	2005	United Kingdom	European	103	190	80.6	NA	(52.0±9.0)	NA	30.0±6.0	NA	Population based	not describled	TaqMan
Liu et al ²⁸	2006	China	Asian	76	42	88.2	88.1	(44.3±9.8)	(41.7±10.1)	26.3±3.5	25.7±3.3	Hospital based	BMI	PCR-RFLP
Karkucak et al ²³	2012	Turkish	European	69	42	75.4	69.1	(49.8±11.3)	(50.6±10.7)	31.1±4.1	28.5±4.3	Hospital based	age, gender and BMI	PCR-RFLP
Almpanidou et al ²⁴	2012	Greece	European	220	319	90	87.1	(51.0±12.4)	(50.6±13.8)	31.4±5.2	29.6±4.3	Population based	age, race and gender	PCR-RFLP
Li et al ²¹	2013	China	Asian	155	100	100	100	(45.0±9.0)	(46.3±8.0)	29.4±2.1	24.1±2.3	Population based	not describled	TaqMan
Bhushan et al ²⁶	2009	Indians	Asian	104	103	80.8	63.1	(46.2±10.7)	(44.0±10.0)	31.5±4.3	30.9±4.3	Hospital based	age and BMI	PCR-RFLP
Guan et al ²²	2013	China	Asian	531	162	85.1	77.8	(43.6±11.7)	(42.6±13.1)	27.4±3.4	26.9±3.7	Hospital based	age, gender and BMI	PCR-RFLP
Li et al ²⁹	2006	China	Asian	24	48	91.7	87.5	(39.7±7.9)	(38.3±9.2)	30.6±4.6	29.7±4.6	Hospital based	age, race, gender and BMI	TaqMan

NA: Not applicable; BMI: Body mass index; PCR-RFLP: Polymerase chain reaction–restriction fragment length polymorphism.