Table 2.
Allelic association of HOXA1 rs10951154, OSR1 rs12329305, and near FOXF1 rs9936833 single nucleotide polymorphisms (SNPs) with stillborn/neonatal death due to malformations/genetic disorders. (No of cases: 140; No of controls: 200).
| SNP (gene) | Base change | Location | MAF*-cases | MAF*-controls | χ2 | p-value |
|---|---|---|---|---|---|---|
| rs10951154 (HOXA1) | A>G** | 7p15 | 0.134 | 0.166 | 1.267 | 0.2603 |
| rs12329305 (OSR1) | C>T** | 2p24 | 0.134 | 0.056 | 11.454 | 7×10−4 |
| rs9936833 (near FOXF1) | T>C** | 16q24 | 0.434 | 0.385 | 1.462 | 0.2266 |
*
MAF – minor allele frequency;
**
risk alleles; Values of p were adjusted taking into account the structured ancestral distribution. p<0.0166 was considered statistically significant.