Table 1. Effects of rAg85B to Toll-Like and NOD-Like Receptor.
receptor | No ligand | rAg85B | control (+) |
mTLR2 | 0.1±0.0 | 0.1±0.0 | 2.3±0.1 |
mTLR3 | 0.1±0.0 | 0.1±0.0 | 2.4±0.2 |
mTLR4 | 0.1±0.0 | 0.1±0.0 | 2.7±0.1 |
mTLR5 | 0.1±0.0 | 0.1±0.0 | 2.7±0.1 |
mTLR7 | 0.1±0.0 | 0.1±0.0 | 2.1±0.0 |
mTLR8 | 0.1±0.0 | 0.1±0.0 | 2.3±0.1 |
mTLR9 | 0.1±0.0 | 0.1±0.0 | 2.6±0.1 |
mNOD1 | 0.1±0.0 | 0.1±0.0 | 1.7±0.1 |
mNOD2 | 0.2±0.0 | 0.1±0.0 | 1.6±0.1 |
The results are provided as optical density values (650 nm).
The values represent the means and standard deviations of three screenings.
TLR/NLR ligand screening were performed by InvivoGen, as described in Methods.